How should acute gout and chronic gout be managed?
Acute flare: NSAIDs (indomethacin, naproxen), colchicine (low-dose preferred), or corticosteroids—choice based on comorbidities. Ice and rest. Do not start or stop ULT during acute flare. Chronic management: urate-lowering therapy (ULT) for recurrent flares, tophi, or CKD. Allopurinol first-line, titrate to serum urate <6 mg/dL. Febuxostat if allopurinol intolerant. Prophylaxis with low-dose colchicine or NSAID for 3-6 months when starting ULT.
Alerah Consensus Engine
Multi-Guideline Agreement: High (91%)
Consensus Models: Gemini 3, Gemini 3 Pro, Sonnet 4.5, GPT 5.2
External Auditors: Grok 4, Opus 4.5
Last reconciled: December 31, 2025 | Version: 1.0
Multi-Guideline Agreement: High (91%)
Consensus Models: Gemini 3, Gemini 3 Pro, Sonnet 4.5, GPT 5.2
External Auditors: Grok 4, Opus 4.5
Last reconciled: December 31, 2025 | Version: 1.0
Disclaimer: This consensus summary is for informational purposes only and does not constitute medical advice.