What is the evidence-based approach to GERD management?
Lifestyle modifications (weight loss, head of bed elevation, avoiding triggers) plus PPI therapy for 4-8 weeks as initial approach. Step-down to lowest effective dose or on-demand therapy for maintenance. H2 blockers for mild symptoms. Endoscopy indicated for alarm symptoms, refractory cases, or long-standing symptoms. Fundoplication considered for refractory GERD with proven reflux.
Alerah Consensus Engine
Multi-Guideline Agreement: High (93%)
Consensus Models: Gemini 3, Gemini 3 Pro, Sonnet 4.5, GPT 5.2
External Auditors: Grok 4, Opus 4.5
Last reconciled: December 31, 2025 | Version: 1.0
Multi-Guideline Agreement: High (93%)
Consensus Models: Gemini 3, Gemini 3 Pro, Sonnet 4.5, GPT 5.2
External Auditors: Grok 4, Opus 4.5
Last reconciled: December 31, 2025 | Version: 1.0
Disclaimer: This consensus summary is for informational purposes only and does not constitute medical advice.